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PubMed was developed and is maintained by the National Center for Biotechnology Information (NCBI) at the National Institutes of Health (NIH). Part of the U.S. National Library of Medicine (NLM). it includes free access to MEDLINE for everyone.

Clincial Queries

PubMed Clinical Queries provides specialized searches for clinicians:

Clincial Studies and Systematic Reviews.

Search by Clinical Study

Clinical Study Categories use a specialized search method with built-in search filters that limit retrieval to citations to articles reporting research conducted with specific methodologies, including those that report applied clinical research.

Systemataic Reviews

Finding systematic reviews:

In PubMed, Systematic Reviews cover a broad set of articles that build consensus on biomedical topics. This feature is provided to help clinicians locate systematic reviews and similar articles. A list of related sources on this topic is available.

To find Systematic Reviews:

1. Click Clinical Queries from the PubMed homepage

2. Enter your search terms in the search box

3. Click Search

  • Find Systematic Reviews on inhalation therapy for pneumonia.
  • Go to the Clinical Queries page
  • Enter the search terms inhalation therapy pneumonia into the search box, click Search.

Alternatively, enter search terms followed by AND systematic[sb] into the search box. For example, lyme disease AND systematic[sb].

Clinical Studies

To find citations using the Clinical Study Category:

1. Click Clinical Queries from the PubMed homepage.
2. Enter your search terms in the search box
3. Select a Category: Therapy, Diagnosis, Etiology, Prognosis, or Clinical prediction guides
4. Select a Scope: Narrow (specific search) or Broad (sensitive search)
5. Click Search
Find research on diagnosing cystic fibrosis.
  • Go to the Clinical Queries page
  • Enter cystic fibrosis in the search box.
  • Choose “diagnosis” under Category and “narrow” under Scope, click Search.

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